Zydus Vaccine - Product Scorecard

Company: Zydus Cadila

Type: Covid-19 Vaccine
Product (brand name): DNA SARS CoV-2 vaccine (ZyCov-D)
0%
compliance
with criteria
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Explore the results of PAF’s research into the behaviour of Zydus Cadila. Each section is given an overall score; individual criteria are also scored (see icon following the criteria heading).

Click on ‘Explanation about the score’ sign next to each entry to expand and learn more.

Category A: Commitments and Accountability

The company should publicly commit to human rights in relation to product development and marketing, by adopting an official human rights policy statement recognising the right to the highest attainable standard of health. The company should endeavour to integrate human rights into its strategies, policies, programmes, projects, and activities.

The company should also have a publicly available global access plan for their Covid-19 product, based on human rights standards, with measurable targets and lines of accountability.

A1: Does Zydus Cadila publish a global access plan for its product?

Zydus Cadila has made an alliance with Enzychem, through which its vaccine will be supplied to low- and middle-income countries in Latin America and Asian New Southern Policy member countries.

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A2: Does Zydus Cadila commit to comply with human rights standards in relation to product development and marketing?

Zydus Cadila has a human rights policy. It does not mention the UN Guiding Principles on Business and Human Rights or other internationally recognised human rights documents.

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Category C: International cooperation

The company should constructively engage with international initiatives for the equitable distribution of vaccines and therapeutics, such as the Covid-19 Technology Access Pool (C-TAP) or the Medicines Patent Pool (MPP), and the ACT Accelerator (COVAX). The company should also publicly commit to not enforcing the exclusive rights of Covid-19 related patents, and enter into non-exclusive, transparent licensing agreements for its Covid-19 products with other companies.

C1: Does Zydus Cadila commit to C-TAP or MPP?

Zydus Cadila has not committed to C-TAP or the MPP.

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C2: Does Zydus Cadila commit to not enforcing the exclusive rights of Covid-19 related patents?

There is no evidence of Zydus Cadila not enforcing patents.

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C3: Does Zydus Cadila supply to, or signs agreements with, the vaccines or therapeutics pillar of the ACT Accelerator?

ZyCovD has not received WHO Emergency Use Listing, so it cannot yet participate in Covax

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C4: Does Zydus Cadila agree to license its Covid-19 medical products to other companies?

Zydus Cadila has licensed its vaccine to South Korea’s Enzychem Life Sciences to make at least 80 million doses (Cadila will receive license fees and royalty payments)

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Category E: Equality, non-discrimination & equity

The company should engage in efforts to further equitable distribution of Covid-19 vaccines/therapeutics, by equitably distributing its supplies globally, devising fair pricing strategies, and making the active ingredient for its product available to other manufacturers. The company should also engage in full technology transfer to other manufacturers, including the necessary transfer of skills, legal components, knowledge and intellectual property. Where applicable, the company should agree to waive rights in regulatory test data, and refrain from enforcing TRIPS+ measures.

E1: Does Zydus Cadila make the active ingredient available on reasonable grounds? [Only for therapeutics]

[Only applies to therapeutics]

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E2: Does Zydus Cadila commit to full technology transfer to other manufacturers?

The company is looking into it and backs the necessity of tech transfer. Zydus Cadila is in talks with other Indian manufacturers about technology transfer, and has already transferred the vaccine technology to South Korea’s Enzychem Life Sciences in exchange for license fees and royalty payments

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E3: Does Zydus Cadila commit to non-profit, ‘fair’, or differential pricing?

The vaccine is priced at 3.57 US dollars per dose in India. There is no evidence of non-profit or differential pricing internationally so far.

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E4: Does Zydus Cadila equitably distribute supplies globally? [Only applies to vaccines]

Zydus Cadila has sold 100% of its doses to India (a middle-income country) so far.

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E5: Does Zydus Cadila not seek protection beyond the minimum criteria in TRIPS, or not enforce TRIPS+ measures? [where applicable]

No information was found on this criterion.

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E6: Does Zydus Cadila agree to waive exclusive rights in regulatory test data? [where applicable]

No information was found on this criterion.

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Category T: Transparency

The company should be as transparent as possible, by publishing its research and development costs, profit margin, average costs of production, and production capacity for its Covid-19 product. It should also disclose the amount of public subsidies received during product development and/or testing. Licensing agreements should also be made publicly available and clinical trials should be registered in public repositories.

T1: Does Zydus Cadila publish its R&D costs?

The company’s expenses are published in its financial reports, but are not specific to research and development and not specific to the Covid-19 vaccine.

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T2: Does Zydus Cadila publish its profit margin?

The company announced April-June quarter results for 2021-2022, which included growth of 29% YoY, mostly driven by sales of Covid drugs. There is no mention of a margin.

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T3: Does Zydus Cadila publish the average and/or marginal costs of production?

It is estimated that DNA vaccines are more expensive to produce than other types of vaccine approved in India, but no specific production costs are published by Zydus Cadila.

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T4: Does Zydus Cadila publish its production capacity?

Zydus plans to produce 10 million doses by October 2021 and 40-50 Million doses by January 2022.

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T5: Does Zydus Cadila publish the public subsidies it received during product development and/or testing?

Zydus’ vaccine was developed with the support of the department of biotechnology (DBT) and the Indian Council of Medical Research (ICMR). However, the company does not publish this on its own website.

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T6: Does Zydus Cadila publish the text of licensing agreements?

The agreement with Enzychem Life sciences is not published.

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T7: Does Zydus Cadila register its clinical trials in public repositories?

Yes, clinical trials and their results are published in the Lancet.

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