Brii BioSciences Therapeutic - Product Scorecard

Company: Brii Biosciences

Type: Covid-19 Therapeutic
Product (brand name): Amubarvimab & Romlusevimab (Brii-196 & Brii-198)
0%
compliance
with criteria
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Explore the results of PAF’s research into the behaviour of Brii Biosciences . Each section is given an overall score; individual criteria are also scored (see icon following the criteria heading).

Click on ‘Explanation about the score’ sign next to each entry to expand and learn more.

Category A: Commitments and Accountability

The company should publicly commit to human rights in relation to product development and marketing, by adopting an official human rights policy statement recognising the right to the highest attainable standard of health. The company should endeavour to integrate human rights into its strategies, policies, programmes, projects, and activities.

The company should also have a publicly available global access plan for their Covid-19 product, based on human rights standards, with measurable targets and lines of accountability.

A1: Does Brii Biosciences publish a global access plan for its product?

Brii Biosciences has not published a global access plan for its product.

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A2: Does Brii Biosciences commit to comply with human rights standards in relation to product development and marketing?

Brii Biosciences has not made a commitment to comply with human rights.

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Category C: International cooperation

The company should constructively engage with international initiatives for the equitable distribution of vaccines and therapeutics, such as the Covid-19 Technology Access Pool (C-TAP) or the Medicines Patent Pool (MPP), and the ACT Accelerator (COVAX). The company should also publicly commit to not enforcing the exclusive rights of Covid-19 related patents, and enter into non-exclusive, transparent licensing agreements for its Covid-19 products with other companies.

C1: Does Brii Biosciences commit to C-TAP or MPP?

Brii Biosciences has not committed to C-TAP or the MPP.

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C2: Does Brii Biosciences commit to not enforcing the exclusive rights of Covid-19 related patents?

Brio Biosciences has not committed to not enforcing the exclusive rights of Covid-19 related patents.

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C3: Does Brii Biosciences supply to, or signs agreements with, the vaccines or therapeutics pillar of the ACT Accelerator?

Brii Biosciences has not signed an agreement with the ACT Accelerator so far.

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C4: Does Brii Biosciences agree to license its Covid-19 medical products to other companies?

Brii Biosciences has partnered with WuXi Biologics for manufacturing. This is dubbed a ‘strategic collaboration’, which grants Brii Bio access to WuXi Biologics’ antibody platform technology. WuXi biologics is then to be the “exclusive development and manufacturing partner of any novel bispecific antibodies discovered from the WuXiBody Platform”.

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Category E: Equality, non-discrimination & equity

The company should engage in efforts to further equitable distribution of Covid-19 vaccines/therapeutics, by equitably distributing its supplies globally, devising fair pricing strategies, and making the active ingredient for its product available to other manufacturers. The company should also engage in full technology transfer to other manufacturers, including the necessary transfer of skills, legal components, knowledge and intellectual property. Where applicable, the company should agree to waive rights in regulatory test data, and refrain from enforcing TRIPS+ measures.

E1: Does Brii Biosciences make the active ingredient available on reasonable grounds? [Only for therapeutics]

No information has been found on this criterion.

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E2: Does Brii Biosciences commit to full technology transfer to other manufacturers?

Brii Bio’s partnership with WuXi Biologics gives access to ‘the entire antibody platform and technology to discover novel bispecific antibodies’.

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E3: Does Brii Biosciences commit to non-profit, ‘fair’, or differential pricing?

Brii Biosciences has not published any information on pricing yet.

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E4: Does Brii Biosciences equitably distribute supplies globally? [Only applies to vaccines]

[Only applies to vaccines]

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E5: Does Brii Biosciences not seek protection beyond the minimum criteria in TRIPS, or not enforce TRIPS+ measures? [where applicable]

No information has been found on this criterion.

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E6: Does Brii Biosciences agree to waive exclusive rights in regulatory test data? [where applicable]

No information has been found on this criterion.

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Category T: Transparency

The company should be as transparent as possible, by publishing its research and development costs, profit margin, average costs of production, and production capacity for its Covid-19 product. It should also disclose the amount of public subsidies received during product development and/or testing. Licensing agreements should also be made publicly available and clinical trials should be registered in public repositories.

T1: Does Brii Biosciences publish its R&D costs?

Brii Biosciences publishes the overall research and development costs for 2021 in its annual financial report, but these are not specific to Brii-196 and Brii-198.

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T2: Does Brii Biosciences publish its profit margin?

The company publishes its overall profit for 2021 in its annual financial report, but this is not specific to Brii-196 and Brii-198 and does not mention a margin.

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T3: Does Brii Biosciences publish the average and/or marginal costs of production?

Brii Biosciences does not publish the average costs of producing the therapeutic.

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T4: Does Brii Biosciences publish its production capacity?

Brii Bio has secured manufacturing capacity of 1 million doses for 2022 and 2023 each (it has not published in-house production capacity).

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T5: Does Brii Biosciences publish the public subsidies it received during product development and/or testing?

Brii Biosciences has not published any information on public funding.

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T6: Does Brii Biosciences publish the text of licensing agreements?

The agreement with WuXi Biologics is not published.

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T7: Does Brii Biosciences register its clinical trials in public repositories?

Brii Biosciences registers its clinical trials on clinicaltrials.gov and on Brii Bio’s website.

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